If you are using Pix-Star to stream your pictures stored in a Twonky NAS or DLNA server you might have this problem that sometimes the frame disconnects.
This is related to a setting inside the Twonky server with NIC changes.
Go to the ADVANCED section of your Twonky user configuration panel.
inside look down to:
RESTART ON NIC changes.
and below there is a line:
restart on NIC changes.
MAKE SURE TO UNCHECK this!
otherwise the connection might be cut sometimes.
Thank you to Gary for this discovery!